Meiosis and Human Reproduction 

This part of the program will apply what you have learned concerning meiosis to  living systems. Meiosis results in the formation of haploid cells which differentiate into gametes. In some of the lower organisms (Protista) the gametes are physically  identical in size and shape, whereas in the more advanced organisms the gametes are not identical. Read pages indicated by G-14  and study behavioral objective 27. The life cycle of the protist Chlamydomonas (see figure) shows the formation of haploid reproductive cells which fuse together forming a zygote. Note that the reproductive cells (gametes) are physically identical. Draw this life cycle in your notes. These gametes are called isogametes. Reproductive cells produced  in the human life cycle (see figure)  are not physically identical. The female gamete is very large and non motile, whereas; the male gamete is very small and motile in animal organisms / non motile in higher plants organisms. These gametes are called  heterogametes. 

11.  Which of the following statements is false? 

           a. Isogametes are  always genetically identical. 
           b. Heterogametes are haploid. 
           c. Heterogametes are physically different. 
           d. Isogametes are physically identical. 
           e. Isogametes are haploid. 

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  Gametogenisis is the process where meiosis followed by differentiation produces the sex cells in higher animal organisms. This process can be divided into spermatogenesis (formation of sperm) and oogenesis (formation of ovum or egg). Read behavioral objectives 28, 30, and 31. Study  the pages indicated by G-15. Examine the figure showing spermatogenesis. Notice that this process involves both meiosis I and meiosis II. Draw this diagram in your notes and  identify the spermatogonia, primary spermatocyte, secondary spermatocyte, spermatid, sperm. Indicate in your drawing where interphase, prophase I, telophase I, telophase II are located. 
 

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The spermatognium can either divide by mitosis producing more spermatognium or it may be stimulated to undergo meiosis in a step wise fashion forming sperm (spermatogenesis). 

12. Match the correct stage of meiosis I or  II to the correct spermatogenesis term.  Place this question in your notes. (hint: secondary spermatocyte consists of two cells; which stage  of  meiosis consisted of two cells) 

     A. Telophase meiosis II                                  1. spermatid 
     B. Prophase meiosis I                                     2. secondary spermatocyte 
     C. Telophase meiosis I                                    3. primary spermatocyte 
     D. Interphase meiosis I                                    4. spermatogonium 

                                A               B               C               D 
                      a.        1                4                2               3 
                      b.        3                2                4               1 
                      c.        1                3                2               4 
                      d.        3                2                1               4 
 
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13.  If the somatic body cells contain 46 chromosomes, how many chromosomes would be located in  the spermatid? 
 
                      a. 2                              c. 46 
                      b. 23                            d. 92 

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 After spermatogenesis the spermatid differentiates into a sperm. Study behavioral objective 32 and read the pages indicated by G-16. In your notes draw a sperm cell (see below) and indicate the acrosome, nucleus, mitochondria and flagellum. Write a brief function for each of these structures. 

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Spermatogenesis is initiated by the hormone testosterone when the young male reaches puberty and continues throughout his life. In your notes draw the human male reproductive tract and identify the following: testis, seminiferous tubules, interstitial cells, epididymis, vas deferens, urethra.  List a brief description for each of these structures. 

This process is controlled by hormones. In your notes make a chart indicating where each of the following hormones are synthesized (hypothalamus, anterior pituitary, testis)  and what list a function for each hormone. 

  Hormone               Site of Production      Site of Action         Function 
 
GnRH
LN
FSH
Testosterone
 
 

14. Name the  gland which secretes fluids that are basic to neutralize acidity of 
      vagina and contains  factors that  enhance sperm motility. 

      a. urethra                    b. testis              c. prostate           d. scrotum 
 
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15.  Which structure produces  testosterone. 
 
      a. urethra                  b. testis              c. prostate             d. scrotum 

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16.   Which structure in a sperm contains hydrolytic enzymes that  will dissolve protective layers around  the egg ? 

         a. flagellum      b. acrosome       c. centrioles       d. mitochondrion 
 
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17.   Which  structure of  the sperm provides energy for rapid movement? 

         a. flagellum        b. acrosome       c. centrioles      d. mitochondrion 
 
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18.    This male hormone is formed in the pituitary  and stimulates testosterone production. 

        a. GNRH            b. FSH            c LH                 d. estrogen 
 
 
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Read behavioral objectives 29, 30, 34, and 36. Study  the pages indicated by G-17. Examine the figure showing oogenesis. See figure below. Notice that this process involves both meiosis I and meiosis II. Draw this diagram in your notes and  identify the oogonium, primary oocyte, secondary oocyte,  polar bodies, ootid, egg or ovum. Note the differences between oogenesis and spermatogenesis in that only one egg cell is produced during this process and not four. The other three cells form polar bodies which are absorbed and digested by the functional ootid. 
 
 
 

The oogonia  can either divide by mitosis producing more oogonia which than can grow into primary oocytes. Unlike spermatogenesis No oogonia remain after the third month of fetal development, and no new ones form during the rest of  her life. All oogonia which are going to develop into egg cells are formed in the ovaries four months after conception. At birth each of the ovaries contain about a million primary  oocytes. These cells remain at this stage (metaphase I)  until puberty. At this time only a few oocytes resume meiosis during each moth of a female's reproductive span (puberty to metapause)  forming  haploid egg cells. Actually in humans  meiosis II does not occur unless the primary oocyte is fertilized. 

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19.  Match the correct stage of meiosis I or  II to the correct oogenesis term. 

     A. Telophase meiosis II                            1. ootid plus polar cells 
     B. Prophase meiosis I                               2. secondary oocyte plus polar cell 
     C. Telophase meiosis I                              3. primary oocyte 
     D. Interphase meiosis I                              4. oogonium 

                                A               B               C               D 
                      a.        1                4                2               3 
                      b.        3                2                4               1 
                      c.        1                3                2               4 
                      d.        3                2                1               4 
 
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20.   If the somatic body cells contain 24 chromosomes, how many chromosomes 
       would be located in  the ootid? 
 
                      a. 2                              c. 24 
                      b. 12                            d. 48 

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 During oogenesis the secondary oocytes are ovulated from the ovary and move into the oviduct. Read the pages indicated by G-17. In your notes write a paragraph describing what occurs during the development and maturation primary oocytes and follicles and what occurs in the oviduct during fertilization  and if fertilization does not occur. 

 In your notes draw the human female reproductive tract and identify the following: ovaries oviduct, uterus, endometrium tissue of uterus. 

This process is controlled by hormones. In your notes make a chart indicating where each of the following hormones are synthesized (hypothalamus, anterior pituitary, corpus luteum,)  and what list a function for each hormone. Behavioral objective 36. 
 

Hormone                  Site of Production            Site of Action                 Function 
GnRH
LH
FSH
estrogen
progesterone
 

  Only one viable gamete (egg)   is formed during oogenesis with the other three cells (polar bodies)  being absorbed by the final cell (egg). Why do you think that only one egg is formed during  oogenesis? 

   Compare your answer to the answer written below. 

 If  four eggs were formed during oogenesis there would be multiple births (quadruple) instead of single births which would be difficult on the mother.  Multiple births (twins, etc.)  occur when  the oogenesis process occurs two or more time during the same menstrual cycle. 

 
21.  The primary oocyte  is : 

                       a. diploid        b. haploid 
 
 
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22.  How many many eggs are produced by each oogonium? 
 
                       a. 1         b. 2          c. 4          d. 8 

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23.  The polar bodies are : 
 

                         a. diploid       b. haploid 
 
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Read pages indicated by G-18 and   study behavioral objective  35. In your notes explain the events that occur during the menstrual cycle and explain how it is controlled by hormones. 
 

(1)FSH and LH released  by anterior pituitary causes (2) the follicles to grow. (3)Estrogen  produced by follicle cells causing the  continued growth  of follicle, stimulating the  endometrium of uterus to grow and stimulating the  pituitary to release LH and FSH (4). The increase in LH  stimulates  meiosis to continue resulting  in the secondary oocyte and polar body. This culminates in ovulation(5). (6) Corpus luteum secretes  both estrogen and progesterone inhibiting the pituitary and hypothalamus from releasing FSH and LH (7) which prevents the development of more follicle. Corpus luteum breaks down due to lack of LH (8). Estrogen and progesterone droop due to the absence of the corpus luteum.(9). 
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24.   This hormone is produced by the pituitary  and  triggers  the resumption of 
         meiosis  and  culminates  in ovulation. 

        a. FSH                 b. LH                    c. estrogen                 d. progesterone 
 
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25.    The primary hormone that inhibits GnRH is : 

         a. FSH                 b. LH                   c. progesterone           d. estrogen 
 
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 This is the end of miniunit Gamma. Please return to the home front page . You may take the practice test for Gamma. 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

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